Main Story Bosses, in Borderlands 4 are found during the main mission progression of the game. These can be very challenging, and typically have dedicated loot drops. Since these bosses are part of the main storyline of Borderlands 4, they'll usually have unique mechanics and abilities players will need to overcome.
Main Story Boss Tips
- Many bosses have single directional attacks that can be dodged by dashing to the side.
- You can jump and glide over many AoE attacks by holding the jump button to avoid taking extra damage.
- All Story Bosses can be refought using Moxxi's Big Encore Machine for a percentage of your Cash.
- Note: Some Encore Machines will appear immediately after killing the boss for the first time, while others may require you to leave the area entirely before returning.
- When in Ultimate Vault Hunter Mode (UVHM), one of the Encore Machines will be red instead of white. The boss spawned using this enhanced version will have the title "Big Encore" in front of its name. Ex: "Big Encore Splashzone" instead of "Splashzone". This Big Encore version is tougher than normal and can drop some extra special rewards.
- Using the standard Big Encore Machine costs Cash, while using the enhanced red Encore Machine will cost Eridium and can only be done once a week.
List of Main Story Bosses
Main Story Bosses Gallery
Main Story Bosses Table
Search - Main Story Bosses
Name |
Location |
Unique Loot |
|
Riptide Grotto (Coastal Bonescape, Fadefields) | Lead Balloon (Shotgun) Firewerks (Armor) Jelly |
|
Horace’s Oversight (Hungering Plain, Fadefields) | Aegon’s Dream (Assault Rifle) Pacemaker (Repkit) Lucky Clover |
|
The Killing Floors (Dissected Plateau, Fadefields) | Streamer (Heavy Weapon Ordinance) Asher's Rise Blood Analyser |
|
Synthetic Nave (Dissected Plateau, Fadefields) | Budget Deity (Pistol) Waterfall Sho Kunai |
|
Fortress Indomita (Idolator’s Noose, Fadefields) | Golden God (Shotgun) Goremaster Onslaught Dancer (Rafa) Bio-Robot (Gravitar Class Mod) Furnace (Amon) Technomancer (Siren Class Mod) |
|
Cuspid Climb (Terminus Range) | Scrapper Emollient Hoarder (Armor Shield) Linebacker (Shotgun) Hellfire |
|
Lictor’s Black Site (Windspear, Terminus Range) | Rangefinder (Pistol) Heavyweight King's Gambit |
|
Umbral Foundry (Windspear, Terminus Range) | Super Solider Blockbuster Ruby's Grasp Undead Eye (Siren Class Mod) Generator (Gravitar Class Mod) Blacksmith (Amon) Instigator (Rafa) |
|
Moon-Called Throne (Fallen Crown, Carcadia Burn) | Queen's Rest Pandoran Memento Esrimidor (Rafa) Illusionist (Siren Class Mod) Viking (Amon) Skeptic (Gravitar Class Mod) |
|
Elipis Orbital Shatterfield (Fallen Crown, Carcadia Burn) | Ohm I Got Gamma Void |
|
Upper Dominion (Terminus District, Dominion) | Timekeeper's New Shield Borstel Ballista Symmetry |
|
Upper Dominion (Terminus District, Dominion) | Plasma Coil Star Helix |
|
The Phase (Upper Dominion, Terminus District, Dominion) | Coming Soon |
This list is missing Warden Scathe, the very first boss of the game. And Driller Hole. The Boss before the 1st Callis boss fight in the story.
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