To anyone who follows me, I don’t care about nor trust Colossal Biosciences anymore (The people behind the “Wooly Mice”). They have proven themselves to be headline-chasing grifters after this latest stunt. They are claiming to have de-extincted *Aenocyon dirus*, aka the Dire Wolf, by editing just 20 genes from the the DNA of a Grey Wolf (*Canis lupus*) to make this thing:
If it wasn’t clear from their scientific names, Grey Wolves and Dire Wolves aren’t remotely related to one another aside from being Canids, despite what pop culture like Game of Thrones would have you believe. If they did look like each other, it would have had to be via convergent evolution, as they only shared a common ancestor over 5 million years ago.
This distinction, however, isn’t found in the publicized articles about this so-called resurrected Dire Wolf and makes their claim that they brought the Dire Wolf back by simply editing *20* genes from the genome of a Grey Wolf laughable. A Dire Wolf would have shared more in common genetically with a Maned Wolf (*Chrysocyon brachyurus*) or Bush Dog (*Speothos venaticus*) than it would with a Grey Wolf.
Bottom line, don’t fall for whatever this company is trying to tell you. If the Dire Wolf were to be brought back, it wouldn’t be via something like this, and certainly wouldn’t *look* like this. If you want an idea as to how a real Dire Wolf would look like in life, here is some fantastic paleoart by artist Mauricio Antón:
Addendum: I seem to have partially miscalculated Dire Wolf genetics. They were not closer to Maned Wolves or Bush Dogs, but they were still not closely related to Grey Wolves. They were basal members of Canini, related to canids like Jackals (genus Lupulella) but distinct from them. I am sorry for this misinformation in my attempt to correct other misinformation. My main point, however, is still correct.
I’m watching Splash (1984) which is a romcom about a guy who falls in love with a mermaid, and when she chooses a human name she chooses Madison and guy says “that’s not a real name, but alright” which seems to imply that Madison was not a name until at least the 80’s and all girls named Madison are actually named after the mermaid. thought you should know
In light of recent events, let’s not forget that H. Bomberguy is responsible for driving a formerly-beloved transphobic TV writer into a downward spiral that cost him his career and his family… all by playing Donkey Kong.
Finally a good argument for why I’m actually a man
if you told diogenes the cynic about being trans he’d be like “lol that’s a sick troll you’re epic” and you’d be like “diogenes no i’m serious” and he’d be like “lol that’s even better lmao those guys are so mad about it” and then he’d start going by new original neopronouns every single day specifically to piss off the whole symposium
I just had an idea for a really dumb comedy sketch where a transphobe starts ranting about what really makes a women a woman, and diogenes returns each time with a different cis woman or outwardly femme intersex person that doesn’t meet the criteria saying “behold, a man!”
“a woman has XX chromosomes”
*Diogenes with an androgen insensitive XY cis woman*: behold, a man!
“Nono, a woman can bear children!”
*Diogenes with someone who has medical complications associated with pregnancy*: “behold, a man!”
“nono, a woman produces the large gamete”
*Diogenes with a postmenopausal cis woman* “behold, a man!”
attention this is your captain speaking chag sameach pesach to all celebrating and a reminder do not open the airlock to greet elijah the vulcan rabbinic council ruled that opening the door to the room where the seder is occurring is sufficient elijah can get on a starship just fine himself he just likes to be personally invited in to your seder we dont need another incident like last year thank you
Anonymous
