I have commissions open on ko-fi right now! I don’t have a steady source of income at the moment, so I’d be very grateful if you considered commissioning me :D
i wanted to make an oc ask game 😋 things i like to ask people abt their characters:
are they associated with a certain color? what color do they wear the most?
what sort of music would they like? have you thought about what genres or bands do they lean towards? do they have a favorite song?
weapon of choice? any particular reason they chose their weapon?
how crafty/resourceful are they?
how do they typically dress? does their wardrobe lean more towards practicality or aesthetics?
how do they wear their hair? do they care a lot how their hair looks?
favorite animal? why?
do they have a nickname? who gave it to them? if it’s not derived from their real name, what’s the story behind it?
favorite food? least favorite? are they a picky eater? do they have any dietary restrictions?
if they wear jewelry, what kind? do they prefer silver or gold? do they have a favorite gem?
what do they have in common with you? how are they different? would you get along with them?
how long have they been around? do you know their birthday? is their birthday the day you made them or another day? what do they think of celebrating birthdays?
what languages do they speak? how fluently?
are they any good with numbers?
how big or small is their family? who did they live with growing up? do they live with anyone now?
do they have any pets? what do they call their pets?
how did they spend their summers/free time as a child?
their opinion on lying, stealing, and killing?
are they quick to anger? what sets them off?
if applicable, can they drive? if they have their own, what color is their vehicle? is the inside neat and tidy, or a mess?
their favorite place to be?
do they sleep well at night?
how would you describe their voice? can they sing?
do they have any creative hobbies? (art, writing, music, etc)
how good/bad is their hearing? what about their eyesight?
how do they move? are they clumsy? light on their feet? do they use mobility aids?
if applicable, do they have a favorite sport? do they play any sports or prefer to watch?
how do they show that they care about someone? how do they express that they don’t like someone?
are they associated with any particular element (air, earth, fire, water)?
do they smell like anything notable?
do they like receiving gifts? giving gifts? what is their ideal gift?
do they have any habits that aren’t particularly self-destructive, just maybe odd?
if applicable, how would your other characters describe them? i mean specifically the people around them.
how would your character describe themselves? it doesn’t have to line up with how they really are.
the one positive chronic illness thing is that it feels really good to be completely exhausted and then crawl into bed. I love cozy bed time. not that great that it’s happening at 4pm because I walked down the street to buy screws at home hardware, but hey, what can you do.
“Two researchers in the US and Australia have discovered important mechanisms that prevent B cells from attacking the body’s own tissues in autoimmune diseases like arthritis, lupus, and multiple sclerosis—and in the process have won a prestigious prize.
Normally, the body’s immune system protects us from viruses, bacteria, and foreign substances. However, in autoimmune diseases, the immune system starts attacking tissues in the body instead.
Researchers had long tried to discover the cause of autoimmune diseases. But, Christopher Goodnow and David Nemazee, independently of each other, adopted a new approach.
They asked why we do not all develop these diseases. Their focus was on B cells which, together with white blood cells and T cells, are the building blocks of our complex immune system.
“They have given us a new and detailed understanding of the mechanisms that normally prevent faulty B cells from attacking tissues in the body, explaining why most of us are not affected by autoimmune diseases,” says Olle Kämpe, member of the Royal Swedish Academy of Sciences and chair of the Crafoord Prize committee that awarded the pair 6 million Swedish kronor ($600,000).
Neutralize B cells
In recent years, physicians have started to experiment by using existing drugs to neutralize B cells for patients with severe autoimmune diseases, including lupus, rheumatoid arthritis, and multiple sclerosis, which has proven to be very effective at improving their quality of life.
Thanks to this year’s Crafoord Prize Laureates, we have gained fundamental new knowledge about what is happening in the immune system during autoimmune disease attacks.
“This also paves the way for development of new forms of therapies that eventually can cure these diseases—or might prevent them in the future,” said one professor of clinical immunology at the Royal Swedish Academy of Sciences…
More details from the video, since the article glosses over the particulars:
"The laureates discovered what is now called B cell tolerance.
When B cells develop in the bone marrow, not all of them are perfect. To remove the faulty ones, a mechanism starts, in which defective cells are programmed to destroy themself through apoptosis.
The laureates discovered two new mechanisms that are used if some of the bad cells are left. Re-editing, where the immune system alters the combination of receptors, and anergy, that silences B cells with self-reactive receptors.
The laureates were able to demonstrate that these mechanisms sometimes fail. This means that faulty B cells can cause an attack on the body’s own tissues – leading to autoimmune diseases.
Thanks to the laureate’s discoveries, doctors like Anders Bengtsson soon felt able to start treating patients with lupus, arthritis, multiple sclerosis, and many other autoimmune diseases, with medicines that eradicated B cells.
Anders Bengtsson: "I’m very happy that B cells has gotten so much attention because of the laureates. I have seen my patients getting so much better and getting a better life.”
Autoimmune patient: “Today, I feel very good. I really have hope in the research that it will revolutionise things and perhaps even cure it all. That’s what I want, hope for, and believe in.”“
-Article via Good News Network, April 6, 2025. Video via The Royal Swedish Academy of Sciences, January 29, 2025.
Love referring to characters who are never seen without each other as “bonded pairs” like yuuuup. if you put these two in separate cages they’re gonna get real sad and anxious and possibly violent too, one of em is biting the bars as we speak. you gotta adopt both of them or none at all, it is encouraged that you take them both. they are most likely to thrive if they stick together. it is easier for them to get used to new environments and situations because they have each other. they do everything together because they love each other so so much. you COULD separate them but it’s gonna do a lot of psychological damage and it’s gonna lead to a lot of issues and there’s a big possibility they’ll never be the same again
stretched out Creek was meant to dissuade you people from reblogging this post and yet it has not worked, do you WANT him in your house ????
